Aquagenx Antimicrobial Resistant E. coli Kits

**Quantify AMR ESBL E. coli (EC) in 100 mL samples**

Rapid and Robust Test Results for ESBL E. coli in the Field

Antimicrobial Resistance (AMR)

Antimicrobials are medicines used to prevent and treat infections in humans, animals and plants.

Over time, bacteria become resistant to antibiotics and no longer respond to them, which makes infections harder to treat and increases the risk of disease spread, severe illness and death.

A common strain of AMR E. coli is called ESBL (extended-spectrum beta-lactamase-producing) E. coli. These strains are considered critical priority pathogens by the World Health Organization (WHO).

AMR and Water Quality

AMR pathogens flow into water through wastewater systems, discharge from pharmaceutical companies, healthcare facilities, and human waste.

When humans and animals have persistent ESBL E. coli in their gut or consume them, their infected feces can enter drinking water sources, wastewaters, healthcare facility effluent and sewerage, food crop irrigation water, other agricultural waters, poultry and livestock production waters, and recreational waters.

Even properly functioning wastewater treatment systems may not fully remove AMR ESBL E. coli.

Major Global Problem

Antimicrobial resistance poses a major threat to human health around the world and impacts the human, food chain and environment sectors. AMR is a leading cause of death around the world.

According to the WHO, antimicrobial resistance is one of the top global public health and development threats.

It is estimated that bacterial AMR was directly responsible for 1.27 million global deaths in 2019 and contributed to 4.95 million deaths.

WHO Tricycle Protocol

Effective monitoring and surveillance of water is needed to support prevention and control of AMR occurrence and transmission. The WHO Tricycle Protocol encourages countries and other stakeholders to monitor ESBL E. coli in environmental water samples by using a culture based monitoring method (page 31).

The Tricycle Protocol encompasses a cross-sector “One Health” approach to contain this problem, namely by monitoring ESBL E. coli across the human, animal and environmental sectors.

Aquagenx AMR ESBL E. coli Test Kits

Aquagenx’s groundbreaking water quality field tests let anyone monitor AMR ESBL E. coli. Test results with our kits demonstrate excellent correlation to standard culture-based methods in the WHO Tricycle Protocol.

Aquagenx AMR ESBL E. coli water quality test kits quantify ESBL E. coli in 100 mL samples. They are simple tests that are designed for on-site field testing:

No electricity, lab, cold chain or expensive, complicated equipment required
Low cost and portable
Easy to use for field level testing in low resource, rural, disaster/emergency areas
Ambient temperature incubation at 25° Celsius and above
Ambient temperature test results in 20-48 hours
Works at variable temperatures, constant temperature control not required
One-year shelf life of AMR E. coli growth medium
Color change test results easy to interpret
Compact and lightweight, small number of consumables

Who Should Test for AMR E. coli

When humans and animals have persistent ESBL E. coli in their gut or consume them, their infected feces can enter drinking water sources, wastewaters, healthcare facility effluent and sewerage, food crop irrigation water, other agricultural waters, poultry and other livestock production waters, and recreational waters.

Keeping the WHO One Health Framework and Tricycle Initiative in mind, multiple sectors should test for ESBL E. coli in water. Water quality testing for AMR ESBL E. coli should be implemented by:

Government agencies, health and agriculture departments and ministries
Wastewater and sewage treatment operations
Healthcare facilities and hospitals
Poultry and livestock food production facilities
Veterinary and animal agriculture feeding operations
Other agricultural operations, such as for irrigation water
Recreational water operators

CBT AMR EC MPN Kits

Most Probable Number (MPN) in 100 mL

Image: CBT AMR EC MPN Kit 50-Pack

CBT AMR EC MPN Kit 25-Pack
Product Number: CBT-AMR-EC-MPN-25
25 samples

Kit contains:
25 Aquagenx powder growth medium packs
25 100-mL Stand-Up Whirl-Pak® Thio-Bags®
25 Aquagenx Compartment Bags
1 reusable clip to seal compartment bag shut. Extra clips sold separately.

CBT AMR EC MPN Kit 50-Pack
Product Number: CBT-AMR-EC-MPN-50
50 samples

Kit contains:
50 Aquagenx powder growth medium packs
50 100-mL Stand-Up Whirl-Pak Thio-Bags
50 Aquagenx Compartment Bags
2 reusable clips to seal compartment bag shut. Extra clips sold separately.

CBT AMR EC MPN Kit 100-Pack
Product Number: CBT-AMR-EC-MPN-100
100 samples

Kit contains:
100 Aquagenx powder growth medium packs
100 100-mL Stand-Up Whirl-Pak Thio-Bags
100 Aquagenx Compartment Bags
4 reusable clips to seal compartment bag shut. Extra clips sold separately.